HCSGD entry for RNF125
1. General information
| Official gene symbol | RNF125 |
|---|---|
| Entrez ID | 54941 |
| Gene full name | ring finger protein 125, E3 ubiquitin protein ligase |
| Other gene symbols | TRAC-1 TRAC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0032480 | Negative regulation of type I interferon production | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2692571977 | 0.3546810721 | 0.9661062014 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1374000516 |
| GSE13712_SHEAR | Down | -1.5980819429 |
| GSE13712_STATIC | Down | -0.2210979571 |
| GSE19018 | Up | 0.0222708598 |
| GSE19899_A1 | Up | 0.0473089485 |
| GSE19899_A2 | Up | 0.3659866259 |
| PubMed_21979375_A1 | Up | 0.1848886662 |
| PubMed_21979375_A2 | Up | 0.4294573749 |
| GSE35957 | Up | 0.0543421250 |
| GSE36640 | Up | 0.0332425979 |
| GSE54402 | Up | 0.0247637961 |
| GSE9593 | Down | -0.1263547414 |
| GSE43922 | Up | 0.3939107525 |
| GSE24585 | Down | -0.6739536054 |
| GSE37065 | Up | 0.0394527130 |
| GSE28863_A1 | Down | -0.0144321794 |
| GSE28863_A2 | Up | 0.3133174768 |
| GSE28863_A3 | Up | 0.2564571885 |
| GSE28863_A4 | Up | 0.0703706377 |
| GSE48662 | Down | -0.0431989236 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028944 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-151a-3p | MIMAT0000757 | MIRT043614 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044723 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
