HCSGD entry for CDKAL1
1. General information
| Official gene symbol | CDKAL1 |
|---|---|
| Entrez ID | 54901 |
| Gene full name | CDK5 regulatory subunit associated protein 1-like 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005791 | Rough endoplasmic reticulum | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0035598 | N6-threonylcarbomyladenosine methylthiotransferase activity | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | IEA | molecular_function |
| GO:1990145 | Maintenance of translational fidelity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6941276433 | 0.1921153604 | 0.9999902473 | 0.8508943463 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0133304888 |
| GSE13712_SHEAR | Up | 0.5105565550 |
| GSE13712_STATIC | Up | 0.5111265668 |
| GSE19018 | Down | -0.1947477722 |
| GSE19899_A1 | Down | -0.1076000759 |
| GSE19899_A2 | Down | -0.5720248966 |
| PubMed_21979375_A1 | Down | -0.0985612954 |
| PubMed_21979375_A2 | Down | -0.3465517818 |
| GSE35957 | Down | -0.1925365118 |
| GSE36640 | Down | -0.7835324922 |
| GSE54402 | Up | 0.0515236140 |
| GSE9593 | Down | -0.0864519459 |
| GSE43922 | Down | -0.3368091745 |
| GSE24585 | Down | -0.0426899612 |
| GSE37065 | Up | 0.2202901843 |
| GSE28863_A1 | Up | 0.2271372708 |
| GSE28863_A2 | Up | 0.2835245992 |
| GSE28863_A3 | Down | -0.0924556316 |
| GSE28863_A4 | Down | -0.0428288554 |
| GSE48662 | Down | -0.0928335290 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT001643 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027819 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051707 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
