HCSGD entry for LAX1
1. General information
| Official gene symbol | LAX1 |
|---|---|
| Entrez ID | 54900 |
| Gene full name | lymphocyte transmembrane adaptor 1 |
| Other gene symbols | LAX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000188 | Inactivation of MAPK activity | IMP | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006955 | Immune response | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IDA | cellular_component |
| GO:0019901 | Protein kinase binding | IDA | molecular_function |
| GO:0035556 | Intracellular signal transduction | IDA | biological_process |
| GO:0042113 | B cell activation | IDA | biological_process |
| GO:0042169 | SH2 domain binding | IDA | molecular_function |
| GO:0045121 | Membrane raft | IDA | cellular_component |
| GO:0048305 | Immunoglobulin secretion | IEA | biological_process |
| GO:0050851 | Antigen receptor-mediated signaling pathway | IEA | biological_process |
| GO:0050868 | Negative regulation of T cell activation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3735392348 | 0.8848358725 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0195352150 |
| GSE13712_SHEAR | Up | 0.1733235598 |
| GSE13712_STATIC | Down | -0.0790470765 |
| GSE19018 | Up | 0.0362939408 |
| GSE19899_A1 | Up | 0.0628317567 |
| GSE19899_A2 | Up | 0.4242335598 |
| PubMed_21979375_A1 | Up | 0.1912831403 |
| PubMed_21979375_A2 | Down | -0.0673098941 |
| GSE35957 | Up | 0.1312818171 |
| GSE36640 | Down | -0.1856755086 |
| GSE54402 | Down | -0.0673714826 |
| GSE9593 | Up | 0.0321074583 |
| GSE43922 | Up | 0.1077943516 |
| GSE24585 | Up | 0.1083904172 |
| GSE37065 | Up | 0.0903152337 |
| GSE28863_A1 | Down | -0.0256923942 |
| GSE28863_A2 | Up | 0.0794074275 |
| GSE28863_A3 | Up | 0.1785910363 |
| GSE28863_A4 | Up | 0.0368926163 |
| GSE48662 | Up | 0.0637241668 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
