HCSGD entry for ALKBH5
1. General information
| Official gene symbol | ALKBH5 |
|---|---|
| Entrez ID | 54890 |
| Gene full name | alkB, alkylation repair homolog 5 (E. coli) |
| Other gene symbols | ABH5 OFOXD OFOXD1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001666 | Response to hypoxia | IDA | biological_process |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006397 | MRNA processing | IMP | biological_process |
| GO:0006406 | MRNA export from nucleus | IMP | biological_process |
| GO:0007283 | Spermatogenesis | IEA ISS | biological_process |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0016706 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | IDA | molecular_function |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0035515 | Oxidative RNA demethylase activity | IDA | molecular_function |
| GO:0035553 | Oxidative single-stranded RNA demethylation | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1112799666 | 0.9387706964 | 0.6890143496 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1515543244 |
| GSE13712_SHEAR | Down | -0.0727844635 |
| GSE13712_STATIC | Down | -0.0260181345 |
| GSE19018 | Up | 0.6373099114 |
| GSE19899_A1 | Up | 0.1125893051 |
| GSE19899_A2 | Up | 0.3328491789 |
| PubMed_21979375_A1 | Up | 0.3897395126 |
| PubMed_21979375_A2 | Up | 0.7699976919 |
| GSE35957 | Down | -0.3234953386 |
| GSE36640 | Down | -0.0852492813 |
| GSE54402 | Up | 0.1843026558 |
| GSE9593 | Up | 0.1538674437 |
| GSE43922 | Up | 0.4425079038 |
| GSE24585 | Down | -0.0761742209 |
| GSE37065 | Down | -0.1302272808 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.3874469849 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT039912 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042009 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT048722 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049251 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
