HCSGD entry for DEF8
1. General information
| Official gene symbol | DEF8 |
|---|---|
| Entrez ID | 54849 |
| Gene full name | differentially expressed in FDCP 8 homolog (mouse) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0637623495 | 0.9286091106 | 0.5445453602 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3428338055 |
| GSE13712_SHEAR | Up | 0.0299384653 |
| GSE13712_STATIC | Up | 0.1344094852 |
| GSE19018 | Up | 0.0541435091 |
| GSE19899_A1 | Up | 0.2833952272 |
| GSE19899_A2 | Up | 0.5725273085 |
| PubMed_21979375_A1 | Up | 0.9230111206 |
| PubMed_21979375_A2 | Up | 1.0189556632 |
| GSE35957 | Down | -0.0169808561 |
| GSE36640 | Up | 0.2995663955 |
| GSE54402 | Up | 0.3569408443 |
| GSE9593 | Up | 0.2222936798 |
| GSE43922 | Up | 0.1304440771 |
| GSE24585 | Down | -0.3112441776 |
| GSE37065 | Down | -0.0325233321 |
| GSE28863_A1 | Up | 0.0105154765 |
| GSE28863_A2 | Down | -0.1544589607 |
| GSE28863_A3 | Up | 0.1150443024 |
| GSE28863_A4 | Down | -0.0719314350 |
| GSE48662 | Down | -0.2833616667 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1303 | MIMAT0005891 | MIRT035878 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043241 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043288 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
