HCSGD entry for SYTL2
1. General information
| Official gene symbol | SYTL2 |
|---|---|
| Entrez ID | 54843 |
| Gene full name | synaptotagmin-like 2 |
| Other gene symbols | CHR11SYT EXO4 SGA72M SLP2 SLP2A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001786 | Phosphatidylserine binding | IMP | molecular_function |
| GO:0005215 | Transporter activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005546 | Phosphatidylinositol-4,5-bisphosphate binding | IMP | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0006887 | Exocytosis | IDA | biological_process |
| GO:0006904 | Vesicle docking involved in exocytosis | IDA | biological_process |
| GO:0008021 | Synaptic vesicle | IEA | cellular_component |
| GO:0010923 | Negative regulation of phosphatase activity | IDA | biological_process |
| GO:0016020 | Membrane | IEA ISS | cellular_component |
| GO:0016192 | Vesicle-mediated transport | ISS | biological_process |
| GO:0017137 | Rab GTPase binding | IEA | molecular_function |
| GO:0019897 | Extrinsic component of plasma membrane | ISS | cellular_component |
| GO:0019902 | Phosphatase binding | IDA | molecular_function |
| GO:0042043 | Neurexin family protein binding | ISS | molecular_function |
| GO:0042470 | Melanosome | ISS | cellular_component |
| GO:0070382 | Exocytic vesicle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4153728278 | 0.0026576726 | 0.9999902473 | 0.1024196193 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3423964069 |
| GSE13712_SHEAR | Up | 0.3876981591 |
| GSE13712_STATIC | Up | 0.4102318396 |
| GSE19018 | Down | -0.2343762096 |
| GSE19899_A1 | Down | -1.5879681289 |
| GSE19899_A2 | Down | -2.1726159554 |
| PubMed_21979375_A1 | Down | -2.1893852263 |
| PubMed_21979375_A2 | Down | -0.3265914926 |
| GSE35957 | Up | 0.2567415386 |
| GSE36640 | Down | -3.4863216502 |
| GSE54402 | Down | -2.0553699389 |
| GSE9593 | Up | 0.0007213478 |
| GSE43922 | Down | -0.7655372916 |
| GSE24585 | Up | 0.8604141932 |
| GSE37065 | Down | -0.0032548026 |
| GSE28863_A1 | Up | 0.3397048064 |
| GSE28863_A2 | Up | 0.8228549136 |
| GSE28863_A3 | Down | -0.0270022344 |
| GSE28863_A4 | Down | -0.3042575450 |
| GSE48662 | Down | -0.1772855828 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023665 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
