HCSGD entry for ASPN


1. General information

Official gene symbolASPN
Entrez ID54829
Gene full nameasporin
Other gene symbolsOS3 PLAP-1 PLAP1 SLRR1C
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005509Calcium ion bindingIDA IEAmolecular_function
GO:0005518Collagen bindingIEAmolecular_function
GO:0005578Proteinaceous extracellular matrixIDAcellular_component
GO:0030282Bone mineralizationIDAbiological_process
GO:0030512Negative regulation of transforming growth factor beta receptor signaling pathwayIDAbiological_process
GO:0031012Extracellular matrixIDAcellular_component
GO:0070171Negative regulation of tooth mineralizationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33518168000.09860439190.99999024730.6007792130

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3215649475
GSE13712_SHEARDown-0.0360106915
GSE13712_STATICUp0.0653152726
GSE19018Down-0.1029325904
GSE19899_A1Up0.0160116241
GSE19899_A2Down-0.1137910527
PubMed_21979375_A1Down-0.0021504582
PubMed_21979375_A2Down-0.0618682484
GSE35957Up1.2313022658
GSE36640Down-0.0412970374
GSE54402Down-0.0985965705
GSE9593Up0.1151786259
GSE43922Up0.2327138967
GSE24585Up0.0054140368
GSE37065Down-1.3737897898
GSE28863_A1Down-0.4180664476
GSE28863_A2Up0.5096634683
GSE28863_A3Down-0.4790615699
GSE28863_A4Up0.2700713654
GSE48662Down-0.2971851683

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018748MicroarrayFunctional MTI (Weak)18185580
hsa-miR-124-3pMIMAT0000422MIRT023007MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT030089MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.