HCSGD entry for ERCC6L
1. General information
| Official gene symbol | ERCC6L |
|---|---|
| Entrez ID | 54821 |
| Gene full name | excision repair cross-complementing rodent repair deficiency, complementation group 6-like |
| Other gene symbols | PICH RAD26L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000777 | Condensed chromosome kinetochore | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0004386 | Helicase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007067 | Mitosis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9156227993 | 0.0002167927 | 0.9999902473 | 0.0258199095 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6419260616 |
| GSE13712_SHEAR | Down | -0.1616749730 |
| GSE13712_STATIC | Up | 0.1577551370 |
| GSE19018 | Up | 0.0649979724 |
| GSE19899_A1 | Down | -0.3551236775 |
| GSE19899_A2 | Down | -3.8716631247 |
| PubMed_21979375_A1 | Down | -1.6969557672 |
| PubMed_21979375_A2 | Down | -4.7116405646 |
| GSE35957 | Down | -1.6960336015 |
| GSE36640 | Down | -3.9986538068 |
| GSE54402 | Down | -0.7627822034 |
| GSE9593 | Down | -1.1233578366 |
| GSE43922 | Down | -0.5989857983 |
| GSE24585 | Down | -0.2620550049 |
| GSE37065 | Down | -0.2104467081 |
| GSE28863_A1 | Down | -0.2247601102 |
| GSE28863_A2 | Up | 0.9890275942 |
| GSE28863_A3 | Down | -0.5883898859 |
| GSE28863_A4 | Up | 0.5226981729 |
| GSE48662 | Down | -0.5667575746 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024875 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025294 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026175 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028933 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046792 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
