HCSGD entry for NDE1
1. General information
| Official gene symbol | NDE1 |
|---|---|
| Entrez ID | 54820 |
| Gene full name | nudE nuclear distribution E homolog 1 (A. nidulans) |
| Other gene symbols | HOM-TES-87 LIS4 NUDE NUDE1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000132 | Establishment of mitotic spindle orientation | IMP | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000776 | Kinetochore | IDA | cellular_component |
| GO:0000777 | Condensed chromosome kinetochore | IEA | cellular_component |
| GO:0001764 | Neuron migration | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0007020 | Microtubule nucleation | IEA | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007405 | Neuroblast proliferation | IEA | biological_process |
| GO:0008017 | Microtubule binding | IEA ISS | molecular_function |
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0021987 | Cerebral cortex development | IEA IMP | biological_process |
| GO:0031616 | Spindle pole centrosome | IEA ISS | cellular_component |
| GO:0032154 | Cleavage furrow | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IEA | molecular_function |
| GO:0047496 | Vesicle transport along microtubule | IEA | biological_process |
| GO:0051298 | Centrosome duplication | IEA ISS | biological_process |
| GO:0051303 | Establishment of chromosome localization | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9707128453 | 0.0251655066 | 0.9999902473 | 0.3051042377 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1904296673 |
| GSE13712_SHEAR | Down | -0.7492686548 |
| GSE13712_STATIC | Down | -0.4623528909 |
| GSE19018 | Down | -0.0247111540 |
| GSE19899_A1 | Down | -0.0390475055 |
| GSE19899_A2 | Down | -0.2607285958 |
| PubMed_21979375_A1 | Down | -0.4303466471 |
| PubMed_21979375_A2 | Down | -0.7654530356 |
| GSE35957 | Down | -1.0134908560 |
| GSE36640 | Down | -1.2862702199 |
| GSE54402 | Down | -0.1701722617 |
| GSE9593 | Down | -0.2793598570 |
| GSE43922 | Up | 0.1093353564 |
| GSE24585 | Up | 0.2070365122 |
| GSE37065 | Down | -0.1711928303 |
| GSE28863_A1 | Down | -0.1002065009 |
| GSE28863_A2 | Down | -0.1221760189 |
| GSE28863_A3 | Down | -0.2629385941 |
| GSE28863_A4 | Up | 0.3083387189 |
| GSE48662 | Up | 0.1595972203 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022760 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024682 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026541 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028581 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037212 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037412 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-5p | MIMAT0004792 | MIRT037795 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038035 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038356 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039149 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-652-3p | MIMAT0003322 | MIRT039461 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042463 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-151a-3p | MIMAT0000757 | MIRT043599 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043877 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047227 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048448 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048631 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050211 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3196 | MIMAT0015080 | MIRT052813 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
