HCSGD entry for PPID

1. General information

Official gene symbolPPID
Entrez ID5481
Gene full namepeptidylprolyl isomerase D
Other gene symbolsCYP-40 CYPD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIMPbiological_process
GO:0000413Protein peptidyl-prolyl isomerizationIDAbiological_process
GO:0003755Peptidyl-prolyl cis-trans isomerase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmIEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006457Protein foldingISSbiological_process
GO:0006461Protein complex assemblyIDAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0008134Transcription factor bindingIDAmolecular_function
GO:0015031Protein transportIEAbiological_process
GO:0016018Cyclosporin A bindingTASmolecular_function
GO:0019076Viral release from host cellTASbiological_process
GO:0030331Estrogen receptor bindingISSmolecular_function
GO:0030544Hsp70 protein bindingISSmolecular_function
GO:0031072Heat shock protein bindingIPImolecular_function
GO:0034389Lipid particle organizationIMPbiological_process
GO:0043065Positive regulation of apoptotic processIMPbiological_process
GO:0045070Positive regulation of viral genome replicationIMPbiological_process
GO:0045111Intermediate filament cytoskeletonIDAcellular_component
GO:0050714Positive regulation of protein secretionIMPbiological_process
GO:0051879Hsp90 protein bindingIDAmolecular_function
GO:0061077Chaperone-mediated protein foldingIDAbiological_process
GO:0071492Cellular response to UV-AIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72964187150.12457516810.99999024730.6776647448

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4186414101
GSE13712_SHEARUp0.1156432154
GSE13712_STATICDown-0.0778601305
GSE19018Down-0.9935591207
GSE19899_A1Up0.2055002190
GSE19899_A2Down-0.1493466856
PubMed_21979375_A1Down-0.2519857243
PubMed_21979375_A2Down-0.3414105142
GSE35957Down-0.0314529979
GSE36640Down-0.1690622626
GSE54402Down-0.0596358618
GSE9593Down-0.1932440440
GSE43922Up0.2972202930
GSE24585Down-0.4322479581
GSE37065Up0.0519230047
GSE28863_A1Up0.1979694024
GSE28863_A2Down-0.1187875399
GSE28863_A3Up0.1491850087
GSE28863_A4Down-0.2089960499
GSE48662Down-0.3175632090

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30a-5pMIMAT0000087MIRT028395ProteomicsFunctional MTI (Weak)18668040
hsa-let-7b-5pMIMAT0000063MIRT032229ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.