HCSGD entry for PPIC
1. General information
| Official gene symbol | PPIC |
|---|---|
| Entrez ID | 5480 |
| Gene full name | peptidylprolyl isomerase C (cyclophilin C) |
| Other gene symbols | CYPC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003755 | Peptidyl-prolyl cis-trans isomerase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016018 | Cyclosporin A binding | TAS | molecular_function |
| GO:0051082 | Unfolded protein binding | TAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5920045211 | 0.0300173968 | 0.9999902473 | 0.3271319404 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0826660989 |
| GSE13712_SHEAR | Down | -0.1296704055 |
| GSE13712_STATIC | Down | -0.0721709707 |
| GSE19018 | Down | -0.3365384265 |
| GSE19899_A1 | Down | -0.3009323259 |
| GSE19899_A2 | Down | -0.0995857263 |
| PubMed_21979375_A1 | Down | -0.5953365442 |
| PubMed_21979375_A2 | Down | -0.3624889476 |
| GSE35957 | Down | -0.1733205562 |
| GSE36640 | Up | 0.7813798371 |
| GSE54402 | Down | -0.7807130283 |
| GSE9593 | Up | 0.3476075056 |
| GSE43922 | Down | -0.0156383183 |
| GSE24585 | Up | 0.6093739042 |
| GSE37065 | Down | -0.4233026474 |
| GSE28863_A1 | Up | 0.2978371434 |
| GSE28863_A2 | Down | -0.1895568040 |
| GSE28863_A3 | Down | -0.4827887394 |
| GSE28863_A4 | Down | -0.1612088828 |
| GSE48662 | Up | 0.0422964737 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030019 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
