HCSGD entry for ALKBH4
1. General information
| Official gene symbol | ALKBH4 |
|---|---|
| Entrez ID | 54784 |
| Gene full name | alkB, alkylation repair homolog 4 (E. coli) |
| Other gene symbols | ABH4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IDA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006482 | Protein demethylation | IDA | biological_process |
| GO:0016706 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | IDA | molecular_function |
| GO:0030496 | Midbody | IDA | cellular_component |
| GO:0031032 | Actomyosin structure organization | IMP | biological_process |
| GO:0032451 | Demethylase activity | TAS | molecular_function |
| GO:0036090 | Cleavage furrow ingression | IMP | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0070938 | Contractile ring | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7532823791 | 0.3296733103 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0758902016 |
| GSE13712_SHEAR | Up | 0.0610927161 |
| GSE13712_STATIC | Down | -0.1456206972 |
| GSE19018 | Down | -0.2114502838 |
| GSE19899_A1 | Down | -0.0945188911 |
| GSE19899_A2 | Up | 0.6006063192 |
| PubMed_21979375_A1 | Up | 0.0003880165 |
| PubMed_21979375_A2 | Down | -0.3723769627 |
| GSE35957 | Down | -0.0776239966 |
| GSE36640 | Down | -0.3253603844 |
| GSE54402 | Down | -0.0310790608 |
| GSE9593 | Down | -0.0791339301 |
| GSE43922 | Up | 0.0568674940 |
| GSE24585 | Down | -0.1293888914 |
| GSE37065 | Down | -0.0058133389 |
| GSE28863_A1 | Up | 0.0525673211 |
| GSE28863_A2 | Up | 0.0866082117 |
| GSE28863_A3 | Up | 0.2181039927 |
| GSE28863_A4 | Down | -0.1193344581 |
| GSE48662 | Down | -0.0674072757 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029173 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041261 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048965 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
