HCSGD entry for RNF111
1. General information
| Official gene symbol | RNF111 |
|---|---|
| Entrez ID | 54778 |
| Gene full name | ring finger protein 111 |
| Other gene symbols | ARK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000209 | Protein polyubiquitination | IEA | biological_process |
| GO:0004842 | Ubiquitin-protein ligase activity | IEA IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0007389 | Pattern specification process | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0030511 | Positive regulation of transforming growth factor beta receptor signaling pathway | IEA | biological_process |
| GO:0030579 | Ubiquitin-dependent SMAD protein catabolic process | IEA | biological_process |
| GO:0031398 | Positive regulation of protein ubiquitination | IEA | biological_process |
| GO:0032184 | SUMO polymer binding | IDA | molecular_function |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IEA IMP | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0046332 | SMAD binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1184272178 | 0.9199714411 | 0.7060300793 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0290127860 |
| GSE13712_SHEAR | Up | 0.1489234338 |
| GSE13712_STATIC | Down | -0.0076464547 |
| GSE19018 | Up | 0.1557075050 |
| GSE19899_A1 | Up | 0.1797936692 |
| GSE19899_A2 | Up | 0.0765622953 |
| PubMed_21979375_A1 | Up | 1.0826180088 |
| PubMed_21979375_A2 | Up | 0.1475078084 |
| GSE35957 | Down | -0.0628942383 |
| GSE36640 | Up | 0.4799509397 |
| GSE54402 | Down | -0.0477666964 |
| GSE9593 | Up | 0.0747189586 |
| GSE43922 | Up | 0.1674844709 |
| GSE24585 | Up | 0.2877280719 |
| GSE37065 | Up | 0.3818390181 |
| GSE28863_A1 | Up | 0.1444715266 |
| GSE28863_A2 | Up | 0.1607950977 |
| GSE28863_A3 | Down | -0.2936313672 |
| GSE28863_A4 | Down | -0.0110673542 |
| GSE48662 | Down | -0.3224294548 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT021196 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027713 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029993 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031301 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031911 | Microarray | Functional MTI (Weak) | 21199864 |
| hsa-miR-484 | MIMAT0002174 | MIRT042148 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
