HCSGD entry for P4HTM
1. General information
| Official gene symbol | P4HTM |
|---|---|
| Entrez ID | 54681 |
| Gene full name | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| Other gene symbols | EGLN4 HIFPH4 P4H-TM PH-4 PH4 PHD4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016706 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | IEA | molecular_function |
| GO:0031418 | L-ascorbic acid binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3542145397 | 0.1269272178 | 0.9999902473 | 0.6859472593 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1237082654 |
| GSE13712_SHEAR | Down | -0.3788675126 |
| GSE13712_STATIC | Up | 0.1321979770 |
| GSE19018 | Up | 0.1738441836 |
| GSE19899_A1 | Down | -0.9085532762 |
| GSE19899_A2 | Down | -0.2018596113 |
| PubMed_21979375_A1 | Up | 0.0440142306 |
| PubMed_21979375_A2 | Down | -0.0981166915 |
| GSE35957 | Down | -0.1933567332 |
| GSE36640 | Up | 1.3887333791 |
| GSE54402 | Down | -0.7166726538 |
| GSE9593 | Up | 0.3268344186 |
| GSE43922 | Down | -0.1328366317 |
| GSE24585 | Up | 0.1482442015 |
| GSE37065 | Down | -0.0599829731 |
| GSE28863_A1 | Up | 0.1598980678 |
| GSE28863_A2 | Up | 0.0232275891 |
| GSE28863_A3 | Down | -0.1819858261 |
| GSE28863_A4 | Down | -0.1730008738 |
| GSE48662 | Up | 0.6410191096 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vitamin C | DB00126 | NUTR00001 | APRD00084 | EXPT00568 | DB09541 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
