HCSGD entry for CRLS1
1. General information
| Official gene symbol | CRLS1 |
|---|---|
| Entrez ID | 54675 |
| Gene full name | cardiolipin synthase 1 |
| Other gene symbols | C20orf155 CLS CLS1 GCD10 dJ967N21.6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0008654 | Phospholipid biosynthetic process | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016780 | Phosphotransferase activity, for other substituted phosphate groups | IEA | molecular_function |
| GO:0032049 | Cardiolipin biosynthetic process | TAS | biological_process |
| GO:0036148 | Phosphatidylglycerol acyl-chain remodeling | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8690953307 | 0.3261805706 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0437381658 |
| GSE13712_SHEAR | Up | 0.1047713550 |
| GSE13712_STATIC | Down | -0.0920556542 |
| GSE19018 | Down | -0.2399750029 |
| GSE19899_A1 | Up | 0.0673795842 |
| GSE19899_A2 | Up | 0.1375413817 |
| PubMed_21979375_A1 | Up | 0.4896145541 |
| PubMed_21979375_A2 | Down | -0.0072522831 |
| GSE35957 | Down | -0.2566285672 |
| GSE36640 | Down | -0.5573176084 |
| GSE54402 | Down | -0.0195739266 |
| GSE9593 | Down | -0.2130209200 |
| GSE43922 | Up | 0.1585865866 |
| GSE24585 | Down | -0.2391515470 |
| GSE37065 | Down | -0.1190949056 |
| GSE28863_A1 | Up | 0.1791808397 |
| GSE28863_A2 | Down | -0.0242744680 |
| GSE28863_A3 | Down | -0.3759908722 |
| GSE28863_A4 | Up | 0.0913052013 |
| GSE48662 | Down | -0.2034960437 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025804 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
