HCSGD entry for TMEM106B
1. General information
| Official gene symbol | TMEM106B |
|---|---|
| Entrez ID | 54664 |
| Gene full name | transmembrane protein 106B |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005765 | Lysosomal membrane | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031902 | Late endosome membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6231021200 | 0.0745134379 | 0.9999902473 | 0.5144984785 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1513911376 |
| GSE13712_SHEAR | Down | -0.3820118029 |
| GSE13712_STATIC | Up | 0.0078434113 |
| GSE19018 | Up | 0.2845651687 |
| GSE19899_A1 | Down | -0.5912513125 |
| GSE19899_A2 | Down | -0.2891173285 |
| PubMed_21979375_A1 | Down | -0.7496204055 |
| PubMed_21979375_A2 | Down | -0.3413410754 |
| GSE35957 | Up | 0.2311257097 |
| GSE36640 | Up | 0.4511387294 |
| GSE54402 | Down | -0.7515780170 |
| GSE9593 | Up | 0.1525053276 |
| GSE43922 | Down | -0.2613591882 |
| GSE24585 | Up | 0.3164320758 |
| GSE37065 | Up | 0.1680011018 |
| GSE28863_A1 | Up | 0.1720722625 |
| GSE28863_A2 | Up | 0.4167835685 |
| GSE28863_A3 | Down | -0.5849006245 |
| GSE28863_A4 | Down | -0.0862956167 |
| GSE48662 | Down | -0.0215606557 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019872 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037240 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046151 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047527 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
