HCSGD entry for HES2
1. General information
| Official gene symbol | HES2 |
|---|---|
| Entrez ID | 54626 |
| Gene full name | hairy and enhancer of split 2 (Drosophila) |
| Other gene symbols | bHLHb40 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003690 | Double-stranded DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008134 | Transcription factor binding | NAS | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2966968732 | 0.9459392690 | 0.9959645964 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0152253568 |
| GSE13712_SHEAR | Up | 0.3885544543 |
| GSE13712_STATIC | Down | -0.0027922753 |
| GSE19018 | Down | -0.0055718033 |
| GSE19899_A1 | Up | 0.0389295161 |
| GSE19899_A2 | Up | 0.1159759840 |
| PubMed_21979375_A1 | Up | 0.1373804180 |
| PubMed_21979375_A2 | Down | -0.0177148999 |
| GSE35957 | Up | 0.1312814723 |
| GSE36640 | Up | 0.1265439402 |
| GSE54402 | Up | 0.0084869830 |
| GSE9593 | Up | 0.0815915469 |
| GSE43922 | Up | 0.1440289094 |
| GSE24585 | Up | 0.1527433877 |
| GSE37065 | Down | -0.1585932179 |
| GSE28863_A1 | Down | -0.0444006736 |
| GSE28863_A2 | Down | -0.1312109017 |
| GSE28863_A3 | Up | 0.4558080191 |
| GSE28863_A4 | Up | 0.1035198137 |
| GSE48662 | Up | 0.1828974411 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018989 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
