HCSGD entry for NDFIP2
1. General information
| Official gene symbol | NDFIP2 |
|---|---|
| Entrez ID | 54602 |
| Gene full name | Nedd4 family interacting protein 2 |
| Other gene symbols | N4WBP5A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0004871 | Signal transducer activity | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0007165 | Signal transduction | IMP | biological_process |
| GO:0010629 | Negative regulation of gene expression | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031398 | Positive regulation of protein ubiquitination | IMP | biological_process |
| GO:0032410 | Negative regulation of transporter activity | IMP | biological_process |
| GO:0032585 | Multivesicular body membrane | IEA | cellular_component |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IMP | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0050699 | WW domain binding | IPI | molecular_function |
| GO:0051224 | Negative regulation of protein transport | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0116638806 | 0.9409269177 | 0.2718557522 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1194129979 |
| GSE13712_SHEAR | Up | 0.0289800832 |
| GSE13712_STATIC | Up | 0.0627777263 |
| GSE19018 | Up | 0.6232457473 |
| GSE19899_A1 | Up | 0.5847302574 |
| GSE19899_A2 | Up | 0.5098693748 |
| PubMed_21979375_A1 | Up | 0.7405269247 |
| PubMed_21979375_A2 | Up | 0.5722491633 |
| GSE35957 | Up | 0.7875528979 |
| GSE36640 | Up | 1.5187052799 |
| GSE54402 | Up | 0.4155852267 |
| GSE9593 | Up | 0.1452772793 |
| GSE43922 | Up | 0.1942727812 |
| GSE24585 | Up | 0.1608176635 |
| GSE37065 | Down | -0.0140819268 |
| GSE28863_A1 | Up | 0.0231266141 |
| GSE28863_A2 | Down | -0.3311191975 |
| GSE28863_A3 | Down | -0.4076285140 |
| GSE28863_A4 | Up | 0.0912535976 |
| GSE48662 | Down | -0.1686246960 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025956 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026926 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-1914-5p | MIMAT0007889 | MIRT035788 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-760 | MIMAT0004957 | MIRT036778 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043881 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-31-5p | MIMAT0000089 | MIRT049872 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
