HCSGD entry for POU3F2
1. General information
| Official gene symbol | POU3F2 |
|---|---|
| Entrez ID | 5454 |
| Gene full name | POU class 3 homeobox 2 |
| Other gene symbols | BRN2 N-Oct3 OCT7 OTF-7 OTF7 POUF3 brn-2 oct-7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001105 | RNA polymerase II transcription coactivator activity | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0008284 | Positive regulation of cell proliferation | IDA | biological_process |
| GO:0008544 | Epidermis development | IEA | biological_process |
| GO:0014002 | Astrocyte development | IEA | biological_process |
| GO:0021799 | Cerebral cortex radially oriented cell migration | IEA | biological_process |
| GO:0021869 | Forebrain ventricular zone progenitor cell division | IEA | biological_process |
| GO:0021979 | Hypothalamus cell differentiation | IEA | biological_process |
| GO:0021985 | Neurohypophysis development | IEA | biological_process |
| GO:0022011 | Myelination in peripheral nervous system | IEA | biological_process |
| GO:0030182 | Neuron differentiation | IEA | biological_process |
| GO:0040018 | Positive regulation of multicellular organism growth | IEA | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0050770 | Regulation of axonogenesis | IEA | biological_process |
| GO:0071310 | Cellular response to organic substance | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6819880666 | 0.8150913681 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1144813673 |
| GSE13712_SHEAR | Down | -0.1247220365 |
| GSE13712_STATIC | Down | -0.0177092062 |
| GSE19018 | Down | -0.0022127293 |
| GSE19899_A1 | Down | -0.0063940173 |
| GSE19899_A2 | Up | 0.0913224032 |
| PubMed_21979375_A1 | Down | -0.0435992196 |
| PubMed_21979375_A2 | Down | -0.0038329967 |
| GSE35957 | Up | 0.2468177650 |
| GSE36640 | Up | 0.0726355999 |
| GSE54402 | Down | -0.0100100589 |
| GSE9593 | Up | 0.0206426541 |
| GSE43922 | Up | 0.1565459097 |
| GSE24585 | Down | -0.2223739494 |
| GSE37065 | Down | -0.0223997051 |
| GSE28863_A1 | Down | -0.1539310803 |
| GSE28863_A2 | Down | -0.0646844748 |
| GSE28863_A3 | Up | 0.3338466944 |
| GSE28863_A4 | Up | 0.0511811429 |
| GSE48662 | Up | 0.0110091744 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-211-5p | MIMAT0000268 | MIRT006355 | Luciferase reporter assay//Western blot | Functional MTI | 21435193 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT024206 | qRT-PCR | Non-Functional MTI (Weak) | 20516212 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052422 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
