HCSGD entry for ROBO4
1. General information
| Official gene symbol | ROBO4 |
|---|---|
| Entrez ID | 54538 |
| Gene full name | roundabout, axon guidance receptor, homolog 4 (Drosophila) |
| Other gene symbols | ECSM4 MRB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IGI | biological_process |
| GO:0004872 | Receptor activity | IEA TAS | molecular_function |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | TAS | cellular_component |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0030334 | Regulation of cell migration | NAS | biological_process |
| GO:0030336 | Negative regulation of cell migration | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0023165533 | 0.9589544470 | 0.1288493697 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0268374624 |
| GSE13712_SHEAR | Up | 1.1149452310 |
| GSE13712_STATIC | Up | 0.4411158133 |
| GSE19018 | Up | 0.2663299717 |
| GSE19899_A1 | Up | 0.7872492953 |
| GSE19899_A2 | Up | 2.8448238149 |
| PubMed_21979375_A1 | Up | 3.1656289104 |
| PubMed_21979375_A2 | Up | 2.2892249589 |
| GSE35957 | Down | -0.0333758862 |
| GSE36640 | Down | -0.4032861477 |
| GSE54402 | Up | 0.6841378011 |
| GSE9593 | Down | -0.1975496496 |
| GSE43922 | Up | 0.9685283586 |
| GSE24585 | Down | -0.0636897774 |
| GSE37065 | Up | 0.0671031462 |
| GSE28863_A1 | Down | -0.2233577360 |
| GSE28863_A2 | Down | -0.0253190967 |
| GSE28863_A3 | Up | 0.2821179799 |
| GSE28863_A4 | Up | 0.1414620426 |
| GSE48662 | Down | -0.0800597595 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017942 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
