HCSGD entry for POU2F1


1. General information

Official gene symbolPOU2F1
Entrez ID5451
Gene full namePOU class 2 homeobox 1
Other gene symbolsOCT1 OTF1 oct-1B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0006383Transcription from RNA polymerase III promoterTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0030910Olfactory placode formationIEAbiological_process
GO:0043565Sequence-specific DNA bindingIDA IEAmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0060235Lens induction in camera-type eyeIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08970230230.91389464690.62918545161.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0364124036
GSE13712_SHEARUp0.0239289184
GSE13712_STATICUp0.1098334716
GSE19018Up0.1656577922
GSE19899_A1Up0.0733611377
GSE19899_A2Up0.2313181110
PubMed_21979375_A1Up0.3578341179
PubMed_21979375_A2Up0.0622062181
GSE35957Up0.0220799868
GSE36640Down-0.0718015554
GSE54402Up0.1886041344
GSE9593Down-0.0161228991
GSE43922Up0.3048669514
GSE24585Down-0.0172460917
GSE37065Up0.4106700456
GSE28863_A1Up0.8226618004
GSE28863_A2Up0.8170138111
GSE28863_A3Down-0.2310699291
GSE28863_A4Down-0.3602030192
GSE48662Down-0.0528621930

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-9-5pMIMAT0000441MIRT021477MicroarrayFunctional MTI (Weak)17612493
hsa-miR-215-5pMIMAT0000272MIRT024501MicroarrayFunctional MTI (Weak)19074876
hsa-miR-34a-5pMIMAT0000255MIRT025581SequencingFunctional MTI (Weak)20371350
hsa-miR-192-5pMIMAT0000222MIRT026960MicroarrayFunctional MTI (Weak)19074876
hsa-miR-101-3pMIMAT0000099MIRT027386SequencingFunctional MTI (Weak)20371350
hsa-miR-98-5pMIMAT0000096MIRT027851MicroarrayFunctional MTI (Weak)19088304
hsa-miR-26b-5pMIMAT0000083MIRT030341MicroarrayFunctional MTI (Weak)19088304
hsa-miR-324-3pMIMAT0000762MIRT043000CLASHFunctional MTI (Weak)23622248
hsa-miR-15b-5pMIMAT0000417MIRT046392CLASHFunctional MTI (Weak)23622248
hsa-miR-30c-5pMIMAT0000244MIRT047990CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.