HCSGD entry for NLE1
1. General information
| Official gene symbol | NLE1 |
|---|---|
| Entrez ID | 54475 |
| Gene full name | notchless homolog 1 (Drosophila) |
| Other gene symbols | Nle |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001826 | Inner cell mass cell differentiation | IEA | biological_process |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0007219 | Notch signaling pathway | IEA | biological_process |
| GO:0090263 | Positive regulation of canonical Wnt signaling pathway | IEA | biological_process |
| GO:2001268 | Negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8120465180 | 0.0603366285 | 0.9999902473 | 0.4627445221 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0473333931 |
| GSE13712_SHEAR | Up | 0.0245744586 |
| GSE13712_STATIC | Up | 0.0261802626 |
| GSE19018 | Down | -0.1862015739 |
| GSE19899_A1 | Down | -0.0379346099 |
| GSE19899_A2 | Down | -0.1892128171 |
| PubMed_21979375_A1 | Up | 0.7056396586 |
| PubMed_21979375_A2 | Down | -0.1631404522 |
| GSE35957 | Down | -0.1748061805 |
| GSE36640 | Down | -0.7327287285 |
| GSE54402 | Up | 0.0011641261 |
| GSE9593 | Down | -0.3356674129 |
| GSE43922 | Up | 0.0485388682 |
| GSE24585 | Down | -0.8689449424 |
| GSE37065 | Down | -0.3592121264 |
| GSE28863_A1 | Up | 0.5448250224 |
| GSE28863_A2 | Down | -0.2382264948 |
| GSE28863_A3 | Down | -0.1682580391 |
| GSE28863_A4 | Up | 0.0934255214 |
| GSE48662 | Down | -0.0874021613 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019953 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027611 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031827 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032412 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042382 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046828 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT048020 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049402 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
