HCSGD entry for SMCR7L
1. General information
| Official gene symbol | SMCR7L |
|---|---|
| Entrez ID | 54471 |
| Gene full name | Smith-Magenis syndrome chromosome region, candidate 7-like |
| Other gene symbols | HSU79252 MID51 MIEF1 dJ1104E15.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000266 | Mitochondrial fission | IMP | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IDA | cellular_component |
| GO:0005777 | Peroxisome | TAS | cellular_component |
| GO:0008053 | Mitochondrial fusion | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0090141 | Positive regulation of mitochondrial fission | IDA TAS | biological_process |
| GO:0090314 | Positive regulation of protein targeting to membrane | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0017824741 | 0.9907990236 | 0.1123130952 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6133775614 |
| GSE13712_SHEAR | Up | 0.1297632956 |
| GSE13712_STATIC | Up | 0.2841052590 |
| GSE19018 | Down | -0.3285801287 |
| GSE19899_A1 | Up | 0.6061501075 |
| GSE19899_A2 | Up | 1.2362076203 |
| PubMed_21979375_A1 | Up | 0.9257892997 |
| PubMed_21979375_A2 | Up | 1.6448182123 |
| GSE35957 | Up | 0.0909680342 |
| GSE36640 | Up | 0.4304673692 |
| GSE54402 | Up | 0.4017782988 |
| GSE9593 | Up | 0.2644923124 |
| GSE43922 | Up | 0.7409431953 |
| GSE24585 | Down | -0.3894365037 |
| GSE37065 | Up | 0.0602429310 |
| GSE28863_A1 | Up | 0.8483261271 |
| GSE28863_A2 | Up | 0.7107069507 |
| GSE28863_A3 | Up | 0.1167870313 |
| GSE28863_A4 | Up | 0.0492903121 |
| GSE48662 | Up | 0.6153087614 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022899 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT026065 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027750 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032143 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037547 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038354 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-22-5p | MIMAT0004495 | MIRT038964 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-504-5p | MIMAT0002875 | MIRT041090 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041916 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
