HCSGD entry for FBXW5
1. General information
| Official gene symbol | FBXW5 |
|---|---|
| Entrez ID | 54461 |
| Gene full name | F-box and WD repeat domain containing 5 |
| Other gene symbols | Fbw5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IDA IEA | biological_process |
| GO:0019005 | SCF ubiquitin ligase complex | IDA | cellular_component |
| GO:0019901 | Protein kinase binding | IPI | molecular_function |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0043161 | Proteasome-mediated ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0051298 | Centrosome duplication | IMP | biological_process |
| GO:0080008 | Cul4-RING ubiquitin ligase complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2975167813 | 0.3362610007 | 0.9965777043 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2141674641 |
| GSE13712_SHEAR | Down | -0.0610589939 |
| GSE13712_STATIC | Down | -0.0577776858 |
| GSE19018 | Down | -0.1182691449 |
| GSE19899_A1 | Down | -0.3549260232 |
| GSE19899_A2 | Up | 0.0138254583 |
| PubMed_21979375_A1 | Up | 0.9638542396 |
| PubMed_21979375_A2 | Up | 0.9515208029 |
| GSE35957 | Up | 0.3734300244 |
| GSE36640 | Up | 0.1046678914 |
| GSE54402 | Up | 0.0951434915 |
| GSE9593 | Up | 0.2839852022 |
| GSE43922 | Up | 0.0107065147 |
| GSE24585 | Down | -0.2098079565 |
| GSE37065 | Down | -0.1625745169 |
| GSE28863_A1 | Down | -0.1775648740 |
| GSE28863_A2 | Down | -0.3610152534 |
| GSE28863_A3 | Down | -0.3661414608 |
| GSE28863_A4 | Down | -0.0487860638 |
| GSE48662 | Up | 0.3923739689 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
