HCSGD entry for SSH1
1. General information
| Official gene symbol | SSH1 |
|---|---|
| Entrez ID | 54434 |
| Gene full name | slingshot protein phosphatase 1 |
| Other gene symbols | SSH1L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000902 | Cell morphogenesis | IMP | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003779 | Actin binding | IDA | molecular_function |
| GO:0004721 | Phosphoprotein phosphatase activity | IDA IMP | molecular_function |
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006470 | Protein dephosphorylation | IMP | biological_process |
| GO:0008064 | Regulation of actin polymerization or depolymerization | IBA | biological_process |
| GO:0008138 | Protein tyrosine/serine/threonine phosphatase activity | IBA | molecular_function |
| GO:0010591 | Regulation of lamellipodium assembly | IBA | biological_process |
| GO:0016791 | Phosphatase activity | IEA | molecular_function |
| GO:0030027 | Lamellipodium | IEA | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | IEA IMP | biological_process |
| GO:0030496 | Midbody | IEA | cellular_component |
| GO:0032154 | Cleavage furrow | IEA | cellular_component |
| GO:0032268 | Regulation of cellular protein metabolic process | IDA | biological_process |
| GO:0050770 | Regulation of axonogenesis | IBA | biological_process |
| GO:0071318 | Cellular response to ATP | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7838241290 | 0.1791503362 | 0.9999902473 | 0.8196893795 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1604781098 |
| GSE13712_SHEAR | Up | 0.1135936352 |
| GSE13712_STATIC | Down | -0.1030009509 |
| GSE19018 | Up | 0.0237701904 |
| GSE19899_A1 | Down | -0.5495879351 |
| GSE19899_A2 | Up | 0.1435140746 |
| PubMed_21979375_A1 | Down | -1.2747913288 |
| PubMed_21979375_A2 | Up | 0.3147312340 |
| GSE35957 | Up | 0.0867188084 |
| GSE36640 | Down | -0.2854711601 |
| GSE54402 | Up | 0.2043207068 |
| GSE9593 | Up | 0.2321231113 |
| GSE43922 | Down | -0.3328473599 |
| GSE24585 | Down | -0.1516952390 |
| GSE37065 | Up | 0.0133325812 |
| GSE28863_A1 | Up | 0.0517162268 |
| GSE28863_A2 | Up | 0.4102981670 |
| GSE28863_A3 | Down | -0.1663803293 |
| GSE28863_A4 | Down | -0.1366013011 |
| GSE48662 | Up | 0.0250161418 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-218-5p | MIMAT0000275 | MIRT024217 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030159 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036943 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040382 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
