HCSGD entry for DNAJC10
1. General information
| Official gene symbol | DNAJC10 |
|---|---|
| Entrez ID | 54431 |
| Gene full name | DnaJ (Hsp40) homolog, subfamily C, member 10 |
| Other gene symbols | ERdj5 JPDI MTHr PDIA19 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001671 | ATPase activator activity | ISS | molecular_function |
| GO:0001933 | Negative regulation of protein phosphorylation | IDA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | IDA | cellular_component |
| GO:0006662 | Glycerol ether metabolic process | IEA | biological_process |
| GO:0015035 | Protein disulfide oxidoreductase activity | IDA ISS | molecular_function |
| GO:0015036 | Disulfide oxidoreductase activity | ISS | molecular_function |
| GO:0016671 | Oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | ISS | molecular_function |
| GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process | IMP | biological_process |
| GO:0030544 | Hsp70 protein binding | IPI | molecular_function |
| GO:0032781 | Positive regulation of ATPase activity | ISS | biological_process |
| GO:0034663 | Endoplasmic reticulum chaperone complex | IDA | cellular_component |
| GO:0034975 | Protein folding in endoplasmic reticulum | IDA | biological_process |
| GO:0034976 | Response to endoplasmic reticulum stress | IDA | biological_process |
| GO:0045454 | Cell redox homeostasis | IEA | biological_process |
| GO:0051087 | Chaperone binding | IDA | molecular_function |
| GO:0051117 | ATPase binding | IPI | molecular_function |
| GO:0051787 | Misfolded protein binding | IDA | molecular_function |
| GO:0070059 | Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7415904335 | 0.4748872687 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2162251672 |
| GSE13712_SHEAR | Down | -0.0666776608 |
| GSE13712_STATIC | Up | 0.1189667669 |
| GSE19018 | Up | 0.1157846513 |
| GSE19899_A1 | Up | 0.2329556270 |
| GSE19899_A2 | Down | -0.0985296612 |
| PubMed_21979375_A1 | Up | 0.4014251137 |
| PubMed_21979375_A2 | Down | -0.2089109159 |
| GSE35957 | Up | 0.0387282924 |
| GSE36640 | Down | -0.1341806590 |
| GSE54402 | Down | -0.0913185445 |
| GSE9593 | Down | -0.0020963928 |
| GSE43922 | Up | 0.0823227541 |
| GSE24585 | Up | 0.0499862759 |
| GSE37065 | Down | -0.1187179806 |
| GSE28863_A1 | Up | 0.0118725679 |
| GSE28863_A2 | Up | 0.1798449790 |
| GSE28863_A3 | Down | -0.1337827542 |
| GSE28863_A4 | Up | 0.0034687082 |
| GSE48662 | Down | -0.3131190928 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023948 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040460 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
