HCSGD entry for POLR2J

1. General information

Official gene symbolPOLR2J
Entrez ID5439
Gene full namepolymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
Other gene symbolsPOLR2J1 RPB11 RPB11A RPB11m hRPB14
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0001055RNA polymerase II activityIBAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0003899DNA-directed RNA polymerase activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005665DNA-directed RNA polymerase II, core complexIDAcellular_component
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0030275LRR domain bindingIPImolecular_function
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0050434Positive regulation of viral transcriptionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90663447440.14987577220.99999024730.7482660724

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3734777648
GSE13712_SHEARDown-0.2384565751
GSE13712_STATICDown-0.1832061717
GSE19018Down-0.2941135441
GSE19899_A1Down-0.3731446695
GSE19899_A2Up0.0368383557
PubMed_21979375_A1Up0.1149980240
PubMed_21979375_A2Down-0.4851846456
GSE35957Down-0.3769256252
GSE36640Down-0.3255084981
GSE54402Down-0.0041818742
GSE9593Up0.0617429923
GSE43922Up0.0706802325
GSE24585Down-0.0581283880
GSE37065Down-0.1278646158
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0981226515

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022854Proteomics;MicroarrayNon-Functional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.