HCSGD entry for POLR2H

1. General information

Official gene symbolPOLR2H
Entrez ID5437
Gene full namepolymerase (RNA) II (DNA directed) polypeptide H
Other gene symbolsRPABC3 RPB17 RPB8 hsRPB8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0001054RNA polymerase I activityIBAmolecular_function
GO:0001055RNA polymerase II activityIBAmolecular_function
GO:0001056RNA polymerase III activityIBAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005665DNA-directed RNA polymerase II, core complexIDAcellular_component
GO:0005666DNA-directed RNA polymerase III complexIBAcellular_component
GO:0005736DNA-directed RNA polymerase I complexIBAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006360Transcription from RNA polymerase I promoterTASbiological_process
GO:0006361Transcription initiation from RNA polymerase I promoterTASbiological_process
GO:0006362Transcription elongation from RNA polymerase I promoterTASbiological_process
GO:0006363Termination of RNA polymerase I transcriptionTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0006383Transcription from RNA polymerase III promoterTASbiological_process
GO:0006385Transcription elongation from RNA polymerase III promoterTASbiological_process
GO:0006386Termination of RNA polymerase III transcriptionTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0032481Positive regulation of type I interferon productionTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09263114240.28173569390.63896198951.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0683497349
GSE13712_SHEARDown-0.3844083627
GSE13712_STATICDown-0.0288125708
GSE19018Down-0.2385715165
GSE19899_A1Up0.7270085945
GSE19899_A2Up0.7129753392
PubMed_21979375_A1Up1.0415812332
PubMed_21979375_A2Up1.0467297315
GSE35957Down-0.8635085122
GSE36640Down-0.5506809642
GSE54402Up0.5216008939
GSE9593Down-0.4004529234
GSE43922Up0.5037801692
GSE24585Up0.1579218665
GSE37065Up0.1136509780
GSE28863_A1Down-0.5748173878
GSE28863_A2Down-0.0640259155
GSE28863_A3Down-0.2080616512
GSE28863_A4Down-0.0384704665
GSE48662Down-0.1127115763

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029504MicroarrayFunctional MTI (Weak)19088304
hsa-let-7b-5pMIMAT0000063MIRT032336ProteomicsFunctional MTI (Weak)18668040
hsa-miR-10a-5pMIMAT0000253MIRT047603CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.