HCSGD entry for POLR2F

1. General information

Official gene symbolPOLR2F
Entrez ID5435
Gene full namepolymerase (RNA) II (DNA directed) polypeptide F
Other gene symbolsHRBP14.4 POLRF RPABC2 RPB14.4 RPB6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0001054RNA polymerase I activityIBAmolecular_function
GO:0001055RNA polymerase II activityIBAmolecular_function
GO:0001056RNA polymerase III activityIBAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0003899DNA-directed RNA polymerase activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005665DNA-directed RNA polymerase II, core complexIDA IEAcellular_component
GO:0005666DNA-directed RNA polymerase III complexIBAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005736DNA-directed RNA polymerase I complexIBAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006360Transcription from RNA polymerase I promoterIBAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0006383Transcription from RNA polymerase III promoterTASbiological_process
GO:0006385Transcription elongation from RNA polymerase III promoterTASbiological_process
GO:0006386Termination of RNA polymerase III transcriptionTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0032481Positive regulation of type I interferon productionTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.32616033590.69447286960.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2070146043
GSE13712_SHEARDown-0.0215666667
GSE13712_STATICUp0.0800067262
GSE19018Up0.0989386129
GSE19899_A1Up0.1989045512
GSE19899_A2Up0.3677781147
PubMed_21979375_A1Up0.0179221497
PubMed_21979375_A2Up0.2722513308
GSE35957Down-0.2004734269
GSE36640Down-0.1533262701
GSE54402Up0.2809749916
GSE9593Down-0.2191050019
GSE43922Up0.4986511650
GSE24585Down-0.4870894378
GSE37065Up0.0194118624
GSE28863_A1Down-0.3400903514
GSE28863_A2Down-0.1686962037
GSE28863_A3Up0.2086996970
GSE28863_A4Up0.0591424114
GSE48662Down-0.0254510110

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029533MicroarrayFunctional MTI (Weak)19088304
hsa-miR-1296-5pMIMAT0005794MIRT036080CLASHFunctional MTI (Weak)23622248
hsa-miR-378a-5pMIMAT0000731MIRT044006CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044569CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.