HCSGD entry for POLR2E

1. General information

Official gene symbolPOLR2E
Entrez ID5434
Gene full namepolymerase (RNA) II (DNA directed) polypeptide E, 25kDa
Other gene symbolsRPABC1 RPB5 XAP4 hRPB25 hsRPB5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0001054RNA polymerase I activityIBAmolecular_function
GO:0001055RNA polymerase II activityIBAmolecular_function
GO:0001056RNA polymerase III activityIBAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0003899DNA-directed RNA polymerase activityIEA TASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005665DNA-directed RNA polymerase II, core complexIDAcellular_component
GO:0005666DNA-directed RNA polymerase III complexIBAcellular_component
GO:0005736DNA-directed RNA polymerase I complexIBAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006360Transcription from RNA polymerase I promoterIBAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0006383Transcription from RNA polymerase III promoterTASbiological_process
GO:0006385Transcription elongation from RNA polymerase III promoterTASbiological_process
GO:0006386Termination of RNA polymerase III transcriptionTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0032481Positive regulation of type I interferon productionTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71892308800.15634572390.99999024730.7633418290

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1910371532
GSE13712_SHEARUp0.0354923618
GSE13712_STATICUp0.0257738702
GSE19018Up0.0741978061
GSE19899_A1Down-0.8022783799
GSE19899_A2Up0.2251394866
PubMed_21979375_A1Down-0.1900796410
PubMed_21979375_A2Down-0.6600859702
GSE35957Up0.1177946519
GSE36640Down-0.1008358300
GSE54402Up0.1306596297
GSE9593Up0.0126384524
GSE43922Down-0.0495231243
GSE24585Down-0.3114952168
GSE37065Down-0.3073459208
GSE28863_A1Up0.0503427006
GSE28863_A2Down-0.0263512176
GSE28863_A3Up0.0484430046
GSE28863_A4Down-0.0292548736
GSE48662Up0.1305021020

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-7-5pMIMAT0000252MIRT025749MicroarrayFunctional MTI (Weak)19073608
hsa-miR-99a-3pMIMAT0004511MIRT038716CLASHFunctional MTI (Weak)23622248
hsa-miR-339-5pMIMAT0000764MIRT042771CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045424CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.