HCSGD entry for POLR2C

1. General information

Official gene symbolPOLR2C
Entrez ID5432
Gene full namepolymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Other gene symbolsRPB3 RPB31 hRPB33 hsRPB3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0001055RNA polymerase II activityIBAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005665DNA-directed RNA polymerase II, core complexIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0016032Viral processTASbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0050434Positive regulation of viral transcriptionTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51699277760.40235923790.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1808069589
GSE13712_SHEARDown-0.1021129322
GSE13712_STATICUp0.0174904808
GSE19018Down-0.2608863768
GSE19899_A1Up0.1536960697
GSE19899_A2Up0.3743377938
PubMed_21979375_A1Up0.5227146232
PubMed_21979375_A2Up0.0140220821
GSE35957Down-0.0649826506
GSE36640Down-0.0532650080
GSE54402Up0.4467290810
GSE9593Down-0.0722042705
GSE43922Up0.2556207850
GSE24585Down-0.1201683004
GSE37065Down-0.1611093253
GSE28863_A1Down-0.4672685167
GSE28863_A2Down-0.2383812833
GSE28863_A3Down-0.4131432449
GSE28863_A4Up0.0369613645
GSE48662Down-0.0670385627

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7b-5pMIMAT0000063MIRT001607pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-155-5pMIMAT0000646MIRT021037ProteomicsFunctional MTI (Weak)18668040
hsa-miR-30a-5pMIMAT0000087MIRT028639ProteomicsFunctional MTI (Weak)18668040
hsa-miR-193b-3pMIMAT0002819MIRT041266CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042934CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.