HCSGD entry for PNN
1. General information
| Official gene symbol | PNN |
|---|---|
| Entrez ID | 5411 |
| Gene full name | pinin, desmosome associated protein |
| Other gene symbols | DRS DRSP SDK3 memA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | IC | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005198 | Structural molecule activity | NAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005882 | Intermediate filament | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005911 | Cell-cell junction | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0030057 | Desmosome | IEA | cellular_component |
| GO:0035145 | Exon-exon junction complex | IDA | cellular_component |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4105154135 | 0.1733238821 | 0.9999902473 | 0.8060172968 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1408919244 |
| GSE13712_SHEAR | Up | 0.0294586751 |
| GSE13712_STATIC | Down | -0.3153140362 |
| GSE19018 | Down | -0.6503060468 |
| GSE19899_A1 | Up | 0.1929571679 |
| GSE19899_A2 | Down | -0.0542229274 |
| PubMed_21979375_A1 | Down | -0.0788569921 |
| PubMed_21979375_A2 | Up | 0.0173308692 |
| GSE35957 | Up | 0.0382218026 |
| GSE36640 | Down | -0.3213869893 |
| GSE54402 | Down | -0.0672494782 |
| GSE9593 | Down | -0.5223383837 |
| GSE43922 | Up | 0.0279405329 |
| GSE24585 | Down | -0.1211007470 |
| GSE37065 | Up | 0.0013255002 |
| GSE28863_A1 | Down | -0.0133076288 |
| GSE28863_A2 | Up | 0.1776134595 |
| GSE28863_A3 | Up | 0.7955126587 |
| GSE28863_A4 | Up | 0.3538602222 |
| GSE48662 | Down | -0.3956929720 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000893 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000894 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-590-3p | MIMAT0004801 | MIRT016172 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023423 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT023477 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1 | MIMAT0000416 | MIRT023760 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036922 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044620 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
Entries Per Page
Displaying Page of
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
