HCSGD entry for FAM3B


1. General information

Official gene symbolFAM3B
Entrez ID54097
Gene full namefamily with sequence similarity 3, member B
Other gene symbols2-21 C21orf11 C21orf76 ORF9 PANDER
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005125Cytokine activityNASmolecular_function
GO:0005576Extracellular regionNAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0030073Insulin secretionIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74112307660.73595780180.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0612668806
GSE13712_SHEARDown-0.0299929172
GSE13712_STATICDown-0.0252364282
GSE19018Down-0.0359164311
GSE19899_A1Up0.0624527689
GSE19899_A2Up0.0422920556
PubMed_21979375_A1Up0.0623030986
PubMed_21979375_A2Up0.1507716743
GSE35957Up0.1103270557
GSE36640Up0.1709157282
GSE54402Down-0.0677647213
GSE9593Down-0.0627604323
GSE43922Up0.0100817171
GSE24585Down-0.4380279185
GSE37065Up0.0390910801
GSE28863_A1Down-0.0469676003
GSE28863_A2Down-0.0478623797
GSE28863_A3Up0.1969009538
GSE28863_A4Up0.0451385781
GSE48662Up0.1243995384

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT019077MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

10454622NHF grown to and left at confluence for 2-21 days showed little (<10%) CpG methylation in the ER and ECAD CpG islands
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