HCSGD entry for CPSF2

1. General information

Official gene symbolCPSF2
Entrez ID53981
Gene full namecleavage and polyadenylation specific factor 2, 100kDa
Other gene symbolsCPSF100
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0003723RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005847MRNA cleavage and polyadenylation specificity factor complexIDA IEAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006369Termination of RNA polymerase II transcriptionTASbiological_process
GO:0006378MRNA polyadenylationIEAbiological_process
GO:0006379MRNA cleavageIEAbiological_process
GO:0006398Histone mRNA 3'-end processingIDAbiological_process
GO:0006406MRNA export from nucleusTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016787Hydrolase activityIEAmolecular_function
GO:0031124MRNA 3'-end processingTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.31436373240.62931940280.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1423826102
GSE13712_SHEARUp0.3842619463
GSE13712_STATICUp0.1766093887
GSE19018Down-0.4051711283
GSE19899_A1Down-0.0277865258
GSE19899_A2Down-0.0537670606
PubMed_21979375_A1Down-0.1136611740
PubMed_21979375_A2Up0.2433756609
GSE35957Up0.1551726496
GSE36640Down-0.3196050733
GSE54402Up0.0688791253
GSE9593Down-0.2395674537
GSE43922Down-0.0491879386
GSE24585Up0.1795025491
GSE37065Down-0.0318045264
GSE28863_A1Up0.2860381584
GSE28863_A2Up0.2604508877
GSE28863_A3Down-0.5276058335
GSE28863_A4Up0.3316073830
GSE48662Down-0.0046856654

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193a-3pMIMAT0000459MIRT044892CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.