HCSGD entry for PRRX1

1. General information

Official gene symbolPRRX1
Entrez ID5396
Gene full namepaired related homeobox 1
Other gene symbolsAGOTC PHOX1 PMX1 PRX-1 PRX1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0002053Positive regulation of mesenchymal cell proliferationIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0003713Transcription coactivator activityTASmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0030326Embryonic limb morphogenesisIEAbiological_process
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0042474Middle ear morphogenesisIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045880Positive regulation of smoothened signaling pathwayIEAbiological_process
GO:0048701Embryonic cranial skeleton morphogenesisIEAbiological_process
GO:0048844Artery morphogenesisIEAbiological_process
GO:0051216Cartilage developmentIEAbiological_process
GO:0060021Palate developmentIEAbiological_process
GO:0071837HMG box domain bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23530737430.00349648570.91885692030.1202554688

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.0323003158
GSE13712_SHEARDown-0.3631029227
GSE13712_STATICUp0.0205479596
GSE19018Down-0.9709749534
GSE19899_A1Down-1.3935763880
GSE19899_A2Down-1.5978495549
PubMed_21979375_A1Down-0.9285008159
PubMed_21979375_A2Down-2.5240553895
GSE35957Up0.0578165063
GSE36640Down-3.4073720316
GSE54402Up0.8828815185
GSE9593Down-0.3012353077
GSE43922Down-1.0767927556
GSE24585Down-0.0152857876
GSE37065Up0.2293184356
GSE28863_A1Up0.5954267197
GSE28863_A2Up1.1713618618
GSE28863_A3Down-0.1630455778
GSE28863_A4Down-0.0285593690
GSE48662Down-0.7796769805

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022167MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.