HCSGD entry for ATP5O
1. General information
| Official gene symbol | ATP5O |
|---|---|
| Entrez ID | 539 |
| Gene full name | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit |
| Other gene symbols | ATPO OSCP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | NAS | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005753 | Mitochondrial proton-transporting ATP synthase complex | IDA NAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006200 | ATP catabolic process | IDA | biological_process |
| GO:0006754 | ATP biosynthetic process | NAS | biological_process |
| GO:0008144 | Drug binding | IDA | molecular_function |
| GO:0015986 | ATP synthesis coupled proton transport | IEA | biological_process |
| GO:0015992 | Proton transport | NAS | biological_process |
| GO:0016887 | ATPase activity | IDA | molecular_function |
| GO:0022857 | Transmembrane transporter activity | IC | molecular_function |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0042776 | Mitochondrial ATP synthesis coupled proton transport | IMP TAS | biological_process |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046933 | Proton-transporting ATP synthase activity, rotational mechanism | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7161364690 | 0.7344162418 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0572111689 |
| GSE13712_SHEAR | Down | -0.0814667006 |
| GSE13712_STATIC | Down | -0.0373310735 |
| GSE19018 | Up | 0.3597449404 |
| GSE19899_A1 | Up | 0.2025819227 |
| GSE19899_A2 | Up | 0.1353453965 |
| PubMed_21979375_A1 | Up | 0.1498423526 |
| PubMed_21979375_A2 | Up | 0.3670250629 |
| GSE35957 | Down | -0.0607911750 |
| GSE36640 | Down | -0.0955747900 |
| GSE54402 | Up | 0.0029712193 |
| GSE9593 | Down | -0.1542326179 |
| GSE43922 | Down | -0.0107593100 |
| GSE24585 | Up | 0.0059782258 |
| GSE37065 | Down | -0.1296271491 |
| GSE28863_A1 | Down | -0.0521343133 |
| GSE28863_A2 | Up | 0.0691178132 |
| GSE28863_A3 | Down | -0.1306572548 |
| GSE28863_A4 | Up | 0.1277830093 |
| GSE48662 | Down | -0.2059766187 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-5p | MIMAT0004949 | MIRT037315 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30e-5p | MIMAT0000692 | MIRT044151 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-182-5p | MIMAT0000259 | MIRT047203 | CLASH | Functional MTI (Weak) | 23622248 |
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