HCSGD entry for FGFRL1
1. General information
| Official gene symbol | FGFRL1 |
|---|---|
| Entrez ID | 53834 |
| Gene full name | fibroblast growth factor receptor-like 1 |
| Other gene symbols | FGFR5 FHFR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001501 | Skeletal system development | IEA | biological_process |
| GO:0003179 | Heart valve morphogenesis | IEA | biological_process |
| GO:0005007 | Fibroblast growth factor-activated receptor activity | IDA IEA | molecular_function |
| GO:0005886 | Plasma membrane | IDA IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0007165 | Signal transduction | IDA | biological_process |
| GO:0008152 | Metabolic process | IDA | biological_process |
| GO:0008201 | Heparin binding | IDA | molecular_function |
| GO:0008285 | Negative regulation of cell proliferation | IEA | biological_process |
| GO:0008543 | Fibroblast growth factor receptor signaling pathway | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016310 | Phosphorylation | IDA | biological_process |
| GO:0017134 | Fibroblast growth factor binding | IEA | molecular_function |
| GO:0018108 | Peptidyl-tyrosine phosphorylation | IDA | biological_process |
| GO:0060412 | Ventricular septum morphogenesis | IEA | biological_process |
| GO:0060539 | Diaphragm development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1565487823 | 0.7774296531 | 0.7854430722 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0990735212 |
| GSE13712_SHEAR | Down | -0.3036557168 |
| GSE13712_STATIC | Down | -0.0901214110 |
| GSE19018 | Up | 0.0061193200 |
| GSE19899_A1 | Down | -0.0362168723 |
| GSE19899_A2 | Up | 0.2641026165 |
| PubMed_21979375_A1 | Up | 0.7483594619 |
| PubMed_21979375_A2 | Up | 0.6441604322 |
| GSE35957 | Down | -0.1465135528 |
| GSE36640 | Up | 0.2970443912 |
| GSE54402 | Up | 0.2577343206 |
| GSE9593 | Down | -0.0502319420 |
| GSE43922 | Up | 0.0932763821 |
| GSE24585 | Down | -0.0348748347 |
| GSE37065 | Down | -0.0338486188 |
| GSE28863_A1 | Up | 0.1409892129 |
| GSE28863_A2 | Up | 0.0310097251 |
| GSE28863_A3 | Up | 0.1083909023 |
| GSE28863_A4 | Down | -0.1149879795 |
| GSE48662 | Up | 0.5255559558 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-210-3p | MIMAT0000267 | MIRT000153 | Luciferase reporter assay//Microarray//qRT-PCR//Western blot | Functional MTI | 21044961 |
| hsa-miR-210-3p | MIMAT0000267 | MIRT000153 | Luciferase reporter assay | Functional MTI | 19782034 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018248 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052346 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
