HCSGD entry for PLXNB3


1. General information

Official gene symbolPLXNB3
Entrez ID5365
Gene full nameplexin B3
Other gene symbolsPLEXB3 PLEXR PLXN6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001938Positive regulation of endothelial cell proliferationIMPbiological_process
GO:0004872Receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007165Signal transductionIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0010593Negative regulation of lamellipodium assemblyISSbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030336Negative regulation of cell migrationIMPbiological_process
GO:0034260Negative regulation of GTPase activityIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22957136890.45455349340.91235814591.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2942358004
GSE13712_SHEARDown-0.2806813997
GSE13712_STATICUp0.0377359068
GSE19018Up0.1759803013
GSE19899_A1Up0.0777096436
GSE19899_A2Up0.2616589783
PubMed_21979375_A1Down-0.0208151706
PubMed_21979375_A2Up0.2533551078
GSE35957Up0.1211480161
GSE36640Up0.0521287924
GSE54402Up0.0492915045
GSE9593Up0.4619817057
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.3782090132

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.