HCSGD entry for PLXNA2
1. General information
| Official gene symbol | PLXNA2 |
|---|---|
| Entrez ID | 5362 |
| Gene full name | plexin A2 |
| Other gene symbols | OCT PLXN2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001756 | Somitogenesis | IEA | biological_process |
| GO:0002116 | Semaphorin receptor complex | TAS | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | ISS | cellular_component |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0017154 | Semaphorin receptor activity | ISS | molecular_function |
| GO:0021915 | Neural tube development | IEA | biological_process |
| GO:0021935 | Cerebellar granule cell precursor tangential migration | IEA | biological_process |
| GO:0030334 | Regulation of cell migration | ISS | biological_process |
| GO:0051642 | Centrosome localization | IEA | biological_process |
| GO:0060037 | Pharyngeal system development | IEA | biological_process |
| GO:0060174 | Limb bud formation | IEA | biological_process |
| GO:0071526 | Semaphorin-plexin signaling pathway | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0052385282 | 0.8869093424 | 0.1888559508 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1447613858 |
| GSE13712_SHEAR | Up | 0.7725978944 |
| GSE13712_STATIC | Up | 0.8523151902 |
| GSE19018 | Up | 0.1077445178 |
| GSE19899_A1 | Up | 0.0736277184 |
| GSE19899_A2 | Up | 0.9879845134 |
| PubMed_21979375_A1 | Up | 0.8211755087 |
| PubMed_21979375_A2 | Up | 0.3090197739 |
| GSE35957 | Down | -0.0878732535 |
| GSE36640 | Up | 0.5348841988 |
| GSE54402 | Up | 0.3440799089 |
| GSE9593 | Down | -0.5110530429 |
| GSE43922 | Up | 0.8757542304 |
| GSE24585 | Down | -1.0696266367 |
| GSE37065 | Up | 0.7237905390 |
| GSE28863_A1 | Up | 0.5264833692 |
| GSE28863_A2 | Up | 0.2740407029 |
| GSE28863_A3 | Down | -0.0675585733 |
| GSE28863_A4 | Up | 0.3510771286 |
| GSE48662 | Up | 0.0794228170 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023176 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030349 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
