HCSGD entry for ADAM22
1. General information
| Official gene symbol | ADAM22 |
|---|---|
| Entrez ID | 53616 |
| Gene full name | ADAM metallopeptidase domain 22 |
| Other gene symbols | ADAM 22 MDC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005178 | Integrin binding | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007162 | Negative regulation of cell adhesion | NAS | biological_process |
| GO:0007417 | Central nervous system development | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008344 | Adult locomotory behavior | IEA | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0022011 | Myelination in peripheral nervous system | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6869606398 | 0.8807278979 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0405946699 |
| GSE13712_SHEAR | Down | -0.0335602713 |
| GSE13712_STATIC | Down | -0.1127480016 |
| GSE19018 | Up | 0.1170213680 |
| GSE19899_A1 | Up | 0.0497816413 |
| GSE19899_A2 | Up | 0.0926616476 |
| PubMed_21979375_A1 | Down | -0.0851270528 |
| PubMed_21979375_A2 | Up | 0.0746116981 |
| GSE35957 | Up | 0.0528227407 |
| GSE36640 | Up | 0.0617448460 |
| GSE54402 | Down | -0.0084849373 |
| GSE9593 | Up | 0.0195018822 |
| GSE43922 | Up | 0.0088003665 |
| GSE24585 | Up | 0.5726897463 |
| GSE37065 | Down | -0.0671360883 |
| GSE28863_A1 | Down | -0.1455810846 |
| GSE28863_A2 | Down | -0.0491362265 |
| GSE28863_A3 | Up | 0.1686404531 |
| GSE28863_A4 | Up | 0.0090425328 |
| GSE48662 | Up | 0.0527093859 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
