HCSGD entry for PLXNA1
1. General information
| Official gene symbol | PLXNA1 |
|---|---|
| Entrez ID | 5361 |
| Gene full name | plexin A1 |
| Other gene symbols | NOV NOVP PLEXIN-A1 PLXN1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002116 | Semaphorin receptor complex | TAS | cellular_component |
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0014910 | Regulation of smooth muscle cell migration | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0017154 | Semaphorin receptor activity | IEA TAS | molecular_function |
| GO:0060666 | Dichotomous subdivision of terminal units involved in salivary gland branching | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1353840280 | 0.2984540557 | 0.7434939362 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0693085214 |
| GSE13712_SHEAR | Up | 0.3135590760 |
| GSE13712_STATIC | Up | 0.3268152063 |
| GSE19018 | Down | -0.1977421659 |
| GSE19899_A1 | Down | -0.1488508818 |
| GSE19899_A2 | Up | 0.3200932570 |
| PubMed_21979375_A1 | Down | -0.1586471330 |
| PubMed_21979375_A2 | Up | 0.3264581274 |
| GSE35957 | Up | 0.0664014507 |
| GSE36640 | Up | 0.5499397568 |
| GSE54402 | Up | 0.0414789056 |
| GSE9593 | Up | 0.4359273857 |
| GSE43922 | Up | 0.2558745082 |
| GSE24585 | Down | -0.9690329223 |
| GSE37065 | Down | -0.3367831281 |
| GSE28863_A1 | Up | 0.5867471452 |
| GSE28863_A2 | Up | 0.6006758984 |
| GSE28863_A3 | Down | -0.2940796025 |
| GSE28863_A4 | Down | -0.3594577262 |
| GSE48662 | Up | 0.0140237922 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018527 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-146a-3p | MIMAT0004608 | MIRT038621 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040286 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041934 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045283 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050583 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050900 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
