HCSGD entry for PLS3
1. General information
| Official gene symbol | PLS3 |
|---|---|
| Entrez ID | 5358 |
| Gene full name | plastin 3 |
| Other gene symbols | T-plastin |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0060348 | Bone development | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9258084305 | 0.0654310778 | 0.9999902473 | 0.4832242985 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1712035400 |
| GSE13712_SHEAR | Up | 0.0908930825 |
| GSE13712_STATIC | Down | -0.0739158695 |
| GSE19018 | Up | 0.2490232874 |
| GSE19899_A1 | Down | -0.1979299030 |
| GSE19899_A2 | Down | -0.1889630939 |
| PubMed_21979375_A1 | Down | -0.3415225300 |
| PubMed_21979375_A2 | Down | -0.2467395346 |
| GSE35957 | Up | 0.1687130729 |
| GSE36640 | Up | 0.0199653398 |
| GSE54402 | Up | 0.2196229594 |
| GSE9593 | Down | -0.0513247717 |
| GSE43922 | Down | -0.1141034369 |
| GSE24585 | Down | -0.7775216125 |
| GSE37065 | Up | 0.0260870342 |
| GSE28863_A1 | Up | 0.0600029649 |
| GSE28863_A2 | Down | -0.0237779135 |
| GSE28863_A3 | Down | -0.6864553881 |
| GSE28863_A4 | Up | 0.2509707075 |
| GSE48662 | Down | -0.7295202441 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023553 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024836 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026136 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-148b-5p | MIMAT0004699 | MIRT038184 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041457 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044656 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045702 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
