HCSGD entry for PLP2
1. General information
| Official gene symbol | PLP2 |
|---|---|
| Entrez ID | 5355 |
| Gene full name | proteolipid protein 2 (colonic epithelium-enriched) |
| Other gene symbols | A4 A4LSB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0006935 | Chemotaxis | NAS | biological_process |
| GO:0015075 | Ion transmembrane transporter activity | TAS | molecular_function |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019221 | Cytokine-mediated signaling pathway | NAS | biological_process |
| GO:0019956 | Chemokine binding | IPI | molecular_function |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3556534744 | 0.1705508909 | 0.9999902473 | 0.7991935197 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1275920260 |
| GSE13712_SHEAR | Down | -0.2136573601 |
| GSE13712_STATIC | Up | 0.0452964095 |
| GSE19018 | Up | 0.1026701762 |
| GSE19899_A1 | Up | 0.3102217108 |
| GSE19899_A2 | Down | -0.2906063590 |
| PubMed_21979375_A1 | Up | 1.1229345286 |
| PubMed_21979375_A2 | Down | -0.2120131842 |
| GSE35957 | Down | -0.4891558275 |
| GSE36640 | Down | -0.4357512389 |
| GSE54402 | Up | 0.2430306016 |
| GSE9593 | Up | 0.1232549953 |
| GSE43922 | Up | 0.1801265224 |
| GSE24585 | Down | -0.2761287077 |
| GSE37065 | Down | -0.0336850826 |
| GSE28863_A1 | Down | -0.2834627498 |
| GSE28863_A2 | Up | 0.4120164106 |
| GSE28863_A3 | Down | -0.2915230820 |
| GSE28863_A4 | Up | 0.0852990684 |
| GSE48662 | Down | -0.5140199392 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002655 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002655 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046849 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
