HCSGD entry for PLCB3
1. General information
Official gene symbol | PLCB3 |
---|---|
Entrez ID | 5331 |
Gene full name | phospholipase C, beta 3 (phosphatidylinositol-specific) |
Other gene symbols | |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0003073 | Regulation of systemic arterial blood pressure | IDA | biological_process |
GO:0004435 | Phosphatidylinositol phospholipase C activity | IEA | molecular_function |
GO:0004629 | Phospholipase C activity | TAS | molecular_function |
GO:0004871 | Signal transducer activity | IEA | molecular_function |
GO:0005509 | Calcium ion binding | IEA | molecular_function |
GO:0005516 | Calmodulin binding | IPI | molecular_function |
GO:0005829 | Cytosol | TAS | cellular_component |
GO:0007268 | Synaptic transmission | TAS | biological_process |
GO:0016020 | Membrane | IEA | cellular_component |
GO:0016042 | Lipid catabolic process | IEA | biological_process |
GO:0035556 | Intracellular signal transduction | IEA | biological_process |
GO:0043234 | Protein complex | IDA | cellular_component |
GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.4858465484 | 0.5746719274 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.0553966975 |
GSE13712_SHEAR | Down | -0.1838342478 |
GSE13712_STATIC | Up | 0.0735223562 |
GSE19018 | Down | -0.2087950692 |
GSE19899_A1 | Up | 0.0198327325 |
GSE19899_A2 | Down | -0.0687846347 |
PubMed_21979375_A1 | Down | -0.2038162341 |
PubMed_21979375_A2 | Up | 0.2445159783 |
GSE35957 | Down | -0.2147434202 |
GSE36640 | Down | -0.1630668610 |
GSE54402 | Up | 0.4573915550 |
GSE9593 | Down | -0.1852962696 |
GSE43922 | Up | 0.0444788774 |
GSE24585 | Up | 0.2285559275 |
GSE37065 | Down | -0.1494628389 |
GSE28863_A1 | Up | 0.1409353762 |
GSE28863_A2 | Up | 0.1726774989 |
GSE28863_A3 | Down | -0.3648339414 |
GSE28863_A4 | Up | 0.0893870405 |
GSE48662 | Down | -0.0054468299 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-1 | MIMAT0000416 | MIRT023858 | Proteomics | Functional MTI (Weak) | 18668040 |
hsa-let-7b-5p | MIMAT0000063 | MIRT032418 | Proteomics | Functional MTI (Weak) | 18668040 |
hsa-miR-197-3p | MIMAT0000227 | MIRT048057 | CLASH | Functional MTI (Weak) | 23622248 |
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