HCSGD entry for PKHD1

1. General information

Official gene symbolPKHD1
Entrez ID5314
Gene full namepolycystic kidney and hepatic disease 1 (autosomal recessive)
Other gene symbolsARPKD FCYT TIGM1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001822Kidney developmentISSbiological_process
GO:0004872Receptor activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0010824Regulation of centrosome duplicationIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIDAcellular_component
GO:0016337Cell-cell adhesionISSbiological_process
GO:0031362Anchored component of external side of plasma membraneTAScellular_component
GO:0036064Ciliary basal bodyIDAcellular_component
GO:0042384Cilium assemblyISSbiological_process
GO:0042592Homeostatic processNASbiological_process
GO:0051271Negative regulation of cellular component movementISSbiological_process
GO:0072372Primary ciliumIDAcellular_component
GO:0072686Mitotic spindleIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92301017820.73845336040.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0052731562
GSE13712_SHEARUp0.0380078238
GSE13712_STATICDown-0.0592813773
GSE19018Up0.1039600261
GSE19899_A1Up0.0315902984
GSE19899_A2Up0.0920221619
PubMed_21979375_A1Down-0.1460847466
PubMed_21979375_A2Down-0.0532226160
GSE35957Up0.0247373327
GSE36640Down-0.0568559455
GSE54402Down-0.1563979238
GSE9593Down-0.1180847726
GSE43922Up0.0384392029
GSE24585Down-0.0519162639
GSE37065Down-0.0080973137
GSE28863_A1Down-0.0329614512
GSE28863_A2Down-0.0074935001
GSE28863_A3Up0.0880228011
GSE28863_A4Up0.0620130067
GSE48662Down-0.0033315202

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.