HCSGD entry for PITPNA
1. General information
| Official gene symbol | PITPNA |
|---|---|
| Entrez ID | 5306 |
| Gene full name | phosphatidylinositol transfer protein, alpha |
| Other gene symbols | PI-TPalpha PITPN VIB1A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006629 | Lipid metabolic process | NAS | biological_process |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0006812 | Cation transport | TAS | biological_process |
| GO:0006820 | Anion transport | TAS | biological_process |
| GO:0006869 | Lipid transport | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0007601 | Visual perception | TAS | biological_process |
| GO:0008289 | Lipid binding | IEA | molecular_function |
| GO:0008525 | Phosphatidylcholine transporter activity | TAS | molecular_function |
| GO:0008526 | Phosphatidylinositol transporter activity | TAS | molecular_function |
| GO:0015695 | Organic cation transport | TAS | biological_process |
| GO:0015697 | Quaternary ammonium group transport | TAS | biological_process |
| GO:0015711 | Organic anion transport | TAS | biological_process |
| GO:0015748 | Organophosphate ester transport | TAS | biological_process |
| GO:0015914 | Phospholipid transport | TAS | biological_process |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0515205121 | 0.9008190114 | 0.4980063900 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3219762907 |
| GSE13712_SHEAR | Down | -0.6581840059 |
| GSE13712_STATIC | Down | -0.1746424784 |
| GSE19018 | Down | -0.2542580294 |
| GSE19899_A1 | Down | -0.1016924517 |
| GSE19899_A2 | Up | 0.5419278003 |
| PubMed_21979375_A1 | Up | 0.5000232501 |
| PubMed_21979375_A2 | Up | 0.8394140643 |
| GSE35957 | Up | 0.0361798995 |
| GSE36640 | Up | 0.6710984615 |
| GSE54402 | Up | 0.4209153253 |
| GSE9593 | Up | 0.1852648121 |
| GSE43922 | Up | 0.0128149956 |
| GSE24585 | Down | -0.0601265593 |
| GSE37065 | Up | 0.0581621040 |
| GSE28863_A1 | Up | 0.3571952877 |
| GSE28863_A2 | Up | 0.0566879379 |
| GSE28863_A3 | Up | 0.4378616824 |
| GSE28863_A4 | Up | 0.2029578489 |
| GSE48662 | Down | -0.0499179329 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 1,2-Diacyl-Sn-Glycero-3-Phosphoinositol | DB02144 | EXPT02597 |
| (Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide | DB03690 | EXPT02526 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT039821 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18b-5p | MIMAT0001412 | MIRT042415 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043471 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049660 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
