HCSGD entry for PI4KB
1. General information
| Official gene symbol | PI4KB |
|---|---|
| Entrez ID | 5298 |
| Gene full name | phosphatidylinositol 4-kinase, catalytic, beta |
| Other gene symbols | NPIK PI4K-BETA PI4K92 PI4KBETA PI4KIIIBETA PIK4CB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0004430 | 1-phosphatidylinositol 4-kinase activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IEA | cellular_component |
| GO:0005768 | Endosome | TAS | cellular_component |
| GO:0005829 | Cytosol | IEA TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | IEA TAS | biological_process |
| GO:0006898 | Receptor-mediated endocytosis | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0030867 | Rough endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0048015 | Phosphatidylinositol-mediated signaling | IEA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0261080886 | 0.9266336651 | 0.3778223749 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4286193201 |
| GSE13712_SHEAR | Up | 0.0928061743 |
| GSE13712_STATIC | Up | 0.2825599240 |
| GSE19018 | Down | -0.1306763317 |
| GSE19899_A1 | Up | 0.1828890562 |
| GSE19899_A2 | Up | 1.1550240745 |
| PubMed_21979375_A1 | Up | 0.7170328076 |
| PubMed_21979375_A2 | Up | 1.5362076794 |
| GSE35957 | Up | 0.0085701949 |
| GSE36640 | Up | 0.6081650059 |
| GSE54402 | Up | 0.2612436925 |
| GSE9593 | Up | 0.0682226315 |
| GSE43922 | Up | 0.2585730967 |
| GSE24585 | Up | 0.0832037841 |
| GSE37065 | Up | 0.0554726492 |
| GSE28863_A1 | Up | 0.1241185432 |
| GSE28863_A2 | Up | 0.2099707166 |
| GSE28863_A3 | Down | -0.7620424957 |
| GSE28863_A4 | Down | -0.3393075132 |
| GSE48662 | Up | 0.0624324378 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-191-5p | MIMAT0000440 | MIRT021489 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036853 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043436 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046289 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050695 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
