HCSGD entry for ATP6V1C1
1. General information
| Official gene symbol | ATP6V1C1 |
|---|---|
| Entrez ID | 528 |
| Gene full name | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| Other gene symbols | ATP6C ATP6D VATC Vma5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA ISS | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0006879 | Cellular iron ion homeostasis | TAS | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | TAS | biological_process |
| GO:0008553 | Hydrogen-exporting ATPase activity, phosphorylative mechanism | IEA | molecular_function |
| GO:0015991 | ATP hydrolysis coupled proton transport | IEA | biological_process |
| GO:0015992 | Proton transport | TAS | biological_process |
| GO:0016469 | Proton-transporting two-sector ATPase complex | TAS | cellular_component |
| GO:0031410 | Cytoplasmic vesicle | IEA | cellular_component |
| GO:0033180 | Proton-transporting V-type ATPase, V1 domain | IEA | cellular_component |
| GO:0033572 | Transferrin transport | TAS | biological_process |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
| GO:0046961 | Proton-transporting ATPase activity, rotational mechanism | TAS | molecular_function |
| GO:0051701 | Interaction with host | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0090382 | Phagosome maturation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0020267733 | 0.9761712283 | 0.1208425339 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6143300979 |
| GSE13712_SHEAR | Up | 0.4057670233 |
| GSE13712_STATIC | Up | 0.2133209422 |
| GSE19018 | Down | -0.0433774569 |
| GSE19899_A1 | Up | 1.2539042655 |
| GSE19899_A2 | Up | 0.9583617282 |
| PubMed_21979375_A1 | Up | 1.0834273564 |
| PubMed_21979375_A2 | Up | 1.1373404683 |
| GSE35957 | Up | 0.3969316788 |
| GSE36640 | Up | 0.5439384435 |
| GSE54402 | Up | 0.7670833246 |
| GSE9593 | Up | 0.7387999891 |
| GSE43922 | Up | 0.6009213713 |
| GSE24585 | Up | 0.1725231003 |
| GSE37065 | Up | 0.2904046850 |
| GSE28863_A1 | Down | -0.3093528942 |
| GSE28863_A2 | Up | 0.7767975914 |
| GSE28863_A3 | Down | -0.7495201692 |
| GSE28863_A4 | Down | -0.2741571317 |
| GSE48662 | Up | 0.0647861126 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| D-tartaric acid | DB01694 | EXPT03007 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001565 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016047 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020236 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021977 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-1 | MIMAT0000416 | MIRT023601 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028462 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031155 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047877 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
