HCSGD entry for PIGC
1. General information
| Official gene symbol | PIGC |
|---|---|
| Entrez ID | 5279 |
| Gene full name | phosphatidylinositol glycan anchor biosynthesis, class C |
| Other gene symbols | GPI2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000506 | Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex | IDA | cellular_component |
| GO:0003824 | Catalytic activity | TAS | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006501 | C-terminal protein lipidation | TAS | biological_process |
| GO:0006506 | GPI anchor biosynthetic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016254 | Preassembly of GPI anchor in ER membrane | TAS | biological_process |
| GO:0017176 | Phosphatidylinositol N-acetylglucosaminyltransferase activity | IEA | molecular_function |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7866333612 | 0.0520070856 | 0.9999902473 | 0.4290670009 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2518909419 |
| GSE13712_SHEAR | Up | 0.3400805557 |
| GSE13712_STATIC | Up | 0.2279013445 |
| GSE19018 | Down | -0.1359137504 |
| GSE19899_A1 | Down | -0.3370660837 |
| GSE19899_A2 | Down | -0.7904192689 |
| PubMed_21979375_A1 | Down | -0.5117474827 |
| PubMed_21979375_A2 | Down | -0.9856555261 |
| GSE35957 | Up | 0.0024857950 |
| GSE36640 | Up | 0.0550902971 |
| GSE54402 | Down | -0.3258476846 |
| GSE9593 | Up | 0.2194880474 |
| GSE43922 | Up | 0.0387208605 |
| GSE24585 | Up | 0.1853087833 |
| GSE37065 | Down | -0.0071925418 |
| GSE28863_A1 | Up | 0.0530669424 |
| GSE28863_A2 | Up | 0.2664489555 |
| GSE28863_A3 | Down | -0.4413318532 |
| GSE28863_A4 | Down | -0.5209049048 |
| GSE48662 | Down | -0.4429234557 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027669 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037438 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
