HCSGD entry for SERPINI1
1. General information
| Official gene symbol | SERPINI1 |
|---|---|
| Entrez ID | 5274 |
| Gene full name | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| Other gene symbols | PI12 neuroserpin |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IBA IEA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0007417 | Central nervous system development | TAS | biological_process |
| GO:0007422 | Peripheral nervous system development | TAS | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0010951 | Negative regulation of endopeptidase activity | IBA | biological_process |
| GO:0030155 | Regulation of cell adhesion | IEA | biological_process |
| GO:0030162 | Regulation of proteolysis | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0000232894 | 0.9835809316 | 0.0149063830 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.3054944082 |
| GSE13712_SHEAR | Up | 0.4499162821 |
| GSE13712_STATIC | Up | 0.8294432143 |
| GSE19018 | Up | 0.4041353751 |
| GSE19899_A1 | Up | 0.7327615446 |
| GSE19899_A2 | Up | 2.7103577077 |
| PubMed_21979375_A1 | Up | 0.4739822040 |
| PubMed_21979375_A2 | Up | 3.2748729474 |
| GSE35957 | Up | 2.0264013350 |
| GSE36640 | Up | 5.5966094782 |
| GSE54402 | Up | 1.6240190073 |
| GSE9593 | Up | 1.1930142056 |
| GSE43922 | Up | 0.7666943596 |
| GSE24585 | Up | 1.6003755646 |
| GSE37065 | Up | 0.4805548650 |
| GSE28863_A1 | Down | -0.5439943018 |
| GSE28863_A2 | Up | 0.0425468853 |
| GSE28863_A3 | Down | -0.2030201179 |
| GSE28863_A4 | Down | -0.0628920946 |
| GSE48662 | Up | 0.2046657638 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030837 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
